In the last few years our knowledge of the human gut microbiota including their development in the early life and their important role in human health is rapidly growing. Human gut is occupied by trillions of microbial cells which have significant effect on metabolism, physiology, nutrition, and immune system. Disruption in the compositional development of the gut microbiota of a newborn has been demonstrated in several studies to predispose to diseases such as obesity, allergy, inflammatory bowel disease, and cardiovascular disease, later in life. Mode of delivery and breastfeeding have been known as the most influential factors of the gut microbiota development. This process is adversely affected by several practices including caesarean section and formula feeding.
Here, we try to find an association of nutritional intake through breastfeeding or formula feeding, gut microbiota profile, and the risk of cardiovascular disease. This will further enhance our understanding of the complexity of the microbiota community in our body. This will provide important information with respect to what create a good gut microbiota as well as expand our understanding of the role of the gut microbiota in human diseases. We will use recently developed genomic tool, next generation sequencing, to study the gut microbiota profile from targeted study population.
